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To address these challenges, various delivery methods have been investigated, including viral vectors, non-viral vectors, and rational design strategies such as chemical modifications, cationic liposomes, polymers, nanocarriers, and biocoupled siRNAs, aimed at enhancing stability and intracellular delivery (Liu F

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Minimize the time the vial spends at room temperature

If patients are eating less and potentially consuming less B12-rich food, supplementing directly alongside the semaglutide injection ensures adequate intake without requiring a separate oral supplement

Acknowledgments The authors would like to express their sincere gratitude to the University of Sunderland for providing the facilities and support that made this work possible