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The sixth coordination site, the center of reactivity, is variable, being a cyano group (-CN), a hydroxyl group (-OH), a methyl group (-CH3) or a 5-deoxyadenosyl group (here the C5 atom of the deoxyribose forms the covalent bond with Co), respectively, to yield the four B12 forms mentioned above

[DOI] [PubMed] [Google Scholar] 91.Parikh U, Marcus C, Sarangi R, Taghipour M, Subramaniam RM

A plant-based diet can contribute if it is not supported with appropriate B12 intake

Developed at Monash University in Australia during the late 1990s, the peptide was engineered to isolate the lipolytic activity of growth hormone from its growth-promoting and diabetogenic effects

B12 also plays a role in maintaining your nerve cells, helping them work properly and keeping your brain sharp