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The blood samples were then separated into EDTA tubes for whole blood collection used for RNA extraction and plain tubes (without anticoagulant) for serum collection

The escalating combinations: High CYP1B1 activity + null GSTM1/GSTT1: CYP1B1 Leu432Val high-activity variants increase 4-OHE2 production from estradiol providing more reactive substrate for quinone formation

Alcohol competes directly with THC for CYP2C9 and CYP3A4 enzymes, potentially extending detection windows by 10-20 days in urine tests

Sci World J 2015:756120

for 2 days at a loading dose of 70 mg/kg per day (Israel et al., 2017)

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