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CoQ10 - up to 1200 mg daily is deemed safe and well tolerated 53

NNMT is over-expressed in a large proportion in renal cell cancers

After that, they are given once a month to keep levels up

The MHRA advises following current clinical guidelines, and it signposts to the NICE Clinical Knowledge Summary (CKS) on this topic (NICE, 2022)

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Chloramphenicol may impair the haematological response to B12 therapy
