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The flavonols quercetin and fisetin (found in fruits and vegetables such as apples, berries, and persimmons) similarly promote neuronal survival and anti-inflammatory effects (20, 21)

Materials and methods Clinical samples of hepatocellular carcinoma patients Human hepatocellular carcinoma (HCC) cancer tumor tissues and matched adjacent tissues ( n = 20) were collected from Cancer Hospital Affiliated to Harbin Medical University for qRT- PCR, western blot and Eliza assays

Any references to neurological or neurochemical pathways are included only to summarize scientific literature and are not claims of safety, efficacy, or suitability for human or animal use

Muscle-specific insulin resistance by the muscle-specific deletion of IRTK or GLUT4 increased the susceptibility to hepatic steatosis, and increase adiposity in animal models [29,30]