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Heres how specific conditions can impact the use of B12 shots: Heart Disease: While B12 is essential for overall health, excessive amounts of vitamin B12 in the body may sometimes cause an increase in certain heart disease risk markers, particularly for individuals with pre-existing cardiovascular conditions

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Titrate: Increase by roughly 100 mcg every 24 weeks as tolerated

Patients with Leber hereditary optic neuropathy should not take methyl B12, since this disease can get worse with high methyl B12 levels

A B12 shot gets absorbed gradually as the muscle tissue releases the nutrient into the bloodstream over hours to days

Rather than relying on supplements alone, these injections deliver vitamin B12 directly into the bloodstream for immediate absorption and faster results