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Mechanisms and outcomes Vitamin B12 interventions are commenced upon diagnosis of low B12 status, typically comprise high dose injections until levels are within acceptable range, and then the intervention is changed to a maintenance dose that is typically administered every 3 months ad infinitum

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When comparing estrogen receptor positive (ER+) and negative (ER-) breast cancers separately IGF-1 was found to be only associated with an increased risk of ER+ breast cancer
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This can lead to dryness and, in turn, infection, irritation, and damage to the eye
