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However, fat stores (i.e., epididymal white adipose tissue) were not significantly depleted in liver-specific Gclc KO mice

Triglycerides are the primary lipid form in the livers of patients with NAFLD (Vatner et al., 2015) The primary transcription factors involved in insulin-mediated fat synthesis are Upstream Stimulator Factor (USF) (Wang and Sul, 1997), sterol regulatory element-binding protein-1c (SREBP-1c) (Raghow et al., 2008), carbohydrate response element-binding protein (ChREBP) (Postic et al., 2007), and liver X receptor alpha (LXR)

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In older people, it can help alleviate the vitamin deficiency that can result from a lack of variety in diet, and can also help maintain energy levels and maintain memory function

Treatment of Obesity