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Priority research needs include large-scale randomized controlled trials to establish efficacy and safety, dose-ranging studies to optimize treatment protocols, long-term safety studies particularly regarding cancer risk, and comparative effectiveness research with established therapies

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Li P, Wang W, Zhou R, Ding Y, Li X
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The oldest mice in the saline control group died at 24 months old and the oldest mice in the Epitalon treated group lived for 34 months [65]
Aebi, H
