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[DOI] [PMC free article] [PubMed] [Google Scholar] 53.Jackson A

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The special feature noted in the present study could be responsible, in particular, for the increased expression and internalization of VEGFR2, which is known to be essential for endothelial function, and the activation of the VEGFR2-Akt-eNOS signaling pathway[25]

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This unique property means both local and systemic administration can support healing, though local injection near the injury typically produces faster results