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Description
Architecture and functional properties of the CFTR channel pore

E2 increased TH promoter activity and expression in the locus coeruleus of female mice but decreased them in males [105]

PMID: 35989070

Moderate deficiency may include obvious macrocytic anemia, glossitis, as well as some mild or subtle neurological features, such as distal sensory impairment.[] Severe deficiency is characterized by bone marrow suppression, neurological features, and the risk of cardiomyopathy

PMID: 25998928
Colombo E, Farina C (2016) Astrocytes: key regulators of neuroinflammation
