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Differences in the single-oral-dose pharmacokinetics and urinary excretion of paracetamol and its conjugates between Hong Kong Chinese and Caucasian subjects

5 T lymphocytes activation by intravenous injection of Con A in mice leads to infiltration of CD4+ T lymphocytes in the liver tissue, and infiltrated CD4+ T lymphocytes secrete a large amount of cytokines such as tumor necrosis factor- (TNF- ), interferon- (IFN- ) and interleukin (IL)-2

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Until full safety data are available, cautious patient selection and baseline risk assessment are advised