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and (2) competition at the enzymes active site with other substrates of kinases that mediate the proper function of the SLC7A11 (xCT) transporter

Lian, H

In this study, we expose cultures of a microglial cell line (SIM-A9) to increasing concentrations of extracellular potassium in the presence of amyloid- to induce inflammation

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Alternatively, accumulation of fat mass secondary to non-GH dependent factors (e.g., lifestyle, dietary habits) results in a feedback inhibition of GH secretion