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Certain medications can contribute to leg cramps, including loop and thiazide diuretics, beta-agonists, and statins (which more commonly cause diffuse myalgia rather than focal cramps)

Its oxidation causes a metabolic shift towards a higher NADH/NAD + ratio that favors enzymatic production of ROS

Bioinformatic profiling identifies a glucose-related risk signature for the malignancy of glioma and the survival of patients

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[Crossref] Zhu X, Lee H, Perry G, Smith MA (2007) Alzheimer disease, the two-hit hypothesis: An update