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IGF-1 and growth hormone receptor activation controls confirming that AOD-9604 does not engage the classical hGH receptor or elevate IGF-1, distinguishing its mechanism from full-length growth hormone in cell-based reporter systems

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Workflow of GRX reduction of glutathionylated proteins Each method offers distinct strengthswhether for targeted validation or comprehensive redox proteome mappingand can be selected based on the study's scale, sensitivity needs, and sample type

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