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Significance of GSTP1 for predicting the prognosis and chemotherapeutic efficacy in esophageal squamous cell carcinoma

These shortcomings are particularly pronounced in the early phase of the disease, where limited predictive accuracy, narrow temporal applicability, and inadequate discriminatory power constrain their clinical utility

Though oral glutathione has a limited bioavailability, supplemental glutathione can be taken orally, intramuscularly, intranasally, topically via cream or intravenously via iv drips

The Pt2/EP1 axis has been shown to inhibit ferroptosis in DOX-induced cardiomyocytes through the PKC/NRF2 signaling pathway, thereby protecting the heart from DIC [45]

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