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Maintaining optimal levels helps ensure these cells remain active and ready

The supplements are generally well-tolerated at doses up to 500 mg daily for up to 2 months

[DOI] [PMC free article] [PubMed] [Google Scholar] 365.Costello LC, et al

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In obesity, dysfunctional adipose tissue induces pathological remodeling, including adipocyte hypertrophy, immune cell infiltration, the release of pro-inflammatory cytokines, impaired angiogenesis, and fibrosis, which collectively contributes to multiorgan inflammation, oxidative stress, insulin resistance, and metabolic dysfunction [33, 34]