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Future research must shift from descriptive association to mechanistic intervention, aiming to target the gut microbiota-metabolite network and thereby establish a new therapeutic paradigm that improves upon the traditional tumor-centric view

These discrepancies point to the fact that the activity of gut metabolites and signaling mediators is highly contextdependent, influenced by variables such as dietary inputs, gut microbiota composition, host health status, and metabolic individuality

Its role as a fat transporter supports metabolic engagement by mobilizing stored fat for energy use, potentially supporting patients in developing leaner physiques over time when combined with appropriate diet and exercise

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VLDL is an important carrier for TGs in the blood

ALC supplementation significantly reduced plasma TC and LDL-C levels in HCD-fed mice and attenuated atherosclerotic progression in LDLR / mice