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This crosslinking is essential for the biomechanical properties of collagen and bone mineralization, which starts in gaps adjacent to crosslinks [53]

and L-carnitine (9 mg/kg, orally) + GW9662 (1 mg/kg per day intraperitoneally) and PDTC (120 mg/kg per day intraperitoneally), a selective inhibitor of nuclear factor (NF)-B, (cat