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Similarly, in chronic myeloid leukaemia (CML), co-inhibition of Trx1 and glutamate-cysteine ligase may serve as a therapeutic strategy for both imatinib-sensitive and drug-resistant patients by triggering ferroptosis (75)

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What is now required are more clinical trials to confirm or disprove these preliminary findings together with closer ties between non-clinical and clinical research to forge a link between molecular mechanisms and therapeutic outcomes

These two substances are precursors to glutathione, one of the bodys most important antioxidants

Wang JG, Yukisada K, Sibulo A Jr, Hafeez K, Jia Y, Zhang J

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