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USA 104 , 1797717982 (2007)

Various oral 5-ASA formulations have been developed to optimize drug delivery to the inflamed colonic mucosa while minimizing systemic side effects [20]

For instance, glutaminolysis, a key mitochondrial metabolic pathway, converts glutamine-derived glutamate into -KG, which fuels the TCA cycle (Wang et al., 2020b)

Notably, BPC-157 counteracts both arterial and venous thrombosis while promoting vessel circumvention in ischemia-reperfusion scenarios
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