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For example, AICAR, a direct activator of AMPK, has been reported to stabilize caspase-8 precursors, enhance RIPK3 degradation, and suppress necroptosis in pancreatic acinar cells, thereby attenuating disease severity and converting SAP in obese mice to a milder form

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S-Beta-hydroxybutyric acid is more rapidly absorbed and utilized by the body than salts or esters, enhances taste, and reduces the need to include citric acid or other edible acids

Liao W, Liu J, Wang S et al (2020) Metabolic profiling reveals that salidroside antagonizes hypoxic injury via modulating energy and lipid metabolism in cardiomyocytes