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A 2020 meta-analysis of 37 randomized trials found an average body-weight reduction of 1.21 kg, with the clearest dose-response signal around 2,000 mg per day

Numerous areas of necrosis with mineralization and cholesterol clefts were associated with extensive hemorrhage surrounded by hemosiderin-laden macrophages

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Regulatory standards for supplement manufacturing are less stringent than those for pharmaceuticals, which contributes to contamination and mislabeling

Case presentation A 34-year-old female patient presented with weakness that progressed over 1 year and progressively involved her entire left upper limb