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doi: 10.4103/0973-3930.60006

It also reflects the growing interest in applying mechanistic strategies to investigate the effects of chemical mixtures on cancer development (39)

The more negative mitochondrial membrane potential of cancer cells as compared with control, nontransformed cells is responsible for enhanced uptake and retention of positively charged drugs conjugated to TPP + 20,21

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Mitochondrial dysfunction: a fatal blow in depression

When fatty acids are activated into acyl-CoA, they undergo -oxidation to primarily produce acetyl-CoA, with simultaneous oxidation and dehydrogenation yielding FADH and NADH