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[DOI] [PubMed] [Google Scholar] Broome MR, Woolley JB, Tabraham P, Johns LC, Bramon E, Murray GK, Pariante C, McGuire PK, Murray RM

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Like hydroquinone, tretinoin can also inhibit tyrosinase

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doi: 10.1038/s41598-021-81384-4 148

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Continuous administration without washout can lead to adaptive downregulationwhere receptors become less responsive to MOTS-c signaling or NNMT inhibition becomes less effective due to compensatory upregulation

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& Kuntz, K

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Recently, it was shown that the IP 3 R1 subtype has a key role in chronic itching (Shiratori-Hayashi et al., 2021) and the absence of IP 3 R2 in astrocytes generates autism spectrum disorder-like behaviors (Wang et al., 2021)

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