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The compound demonstrates blood-brain barrier (BBB) penetration efficiency approximately 1000-fold higher than comparable peptidesa critical factor in determining how frequently administration is required to maintain central nervous system concentrations adequate for receptor engagement

Astroglial cells form a group of functional units inside the CNS integrating synapses, the neurovascular unit and different circuitries

Abstract Antibody-drug conjugates (ADCs) have gained significant attention as a promising therapeutic strategy for non-small cell lung cancer (NSCLC), combining the precision of monoclonal antibodies with the potent cytotoxic effects of chemotherapy

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Data accessed June 2017 and October 2018. www.fda.gov.ph

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