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Even in adulthood, BDNF functions as a neurogenesis and neuronal replacement regulator continues, as demonstrated in neurogenic niches such as the subgranular zone of the hippocampal dentate gyrus, supporting ongoing neuron regeneration and the addition of new neurons into existing neuronal circuits [43]
In addition, higher cytotoxicity of CD8+ cells was observed against melanoma cells after immunization
These abnormalities disrupt neuronal communication, leading to atrophy in areas such as the hippocampus and the neocortex, critical areas for learning and memory [70]
doi: 10.3389/fphar.2014.00159 29 Norouzi-BaroughLSarookhaniMSalehiRSharifiMMoghbelinejadS
Prevalence and trends in obesity among US adults, 1999-2008
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