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A 2025 meta-analysis of 16 studies involving 6,098 participants found no statistically significant difference between intramuscular, oral, and sublingual B12 supplementation routes
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Additional info National Heart, Lung, and Blood Institute (NHLBI) Learn more about Vitamin B12 deficiency Treatment options Care guides Further information Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
In very lean individuals you can actually use insulin syringes to reach the depth of the muscles if you push hard enough on the skin
May 27 2021;doi:10.1039/d1fo00531f Xu ZY, Xu Y, Xie XF, et al
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