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However, since an excess of carbohydrates has been consumed, regulatory measures are taken to slow the TCA cycle, and citrate begins to accumulate

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The only FDA-approved drugs for PrEP at this time are: emtricitabine/tenofovir alafenamide (Descovy) emtricitabine/tenofovir disoproxil fumarate (Truvada) cabotegravir (Apretude) Apretude is an integrase strand transfer inhibitor (INSTI) approved for use as PrEP

Reasons for non-enrollment were mostly due to poor performance status or withheld consent

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