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Currently, the reliance on mitochondrial respiration has been demonstrated in drug-resistant cancer cells and DTP cells from multiple cancer sources

data curation, writingoriginal draft preparation

Chronic and cycling hypoxia: drivers of cancer chronic inflammation through HIF-1 and NF-B activation: a review of the molecular mechanisms

Jiang J, Liu M, Parvez F, Wang B, Wu F, Eunus M, Bangalore S, Newman JD, Ahmed A, Islam T, et al

Hypermethylation of CpG islands in gene promoter regions may cause aberrant silencing of transcription and is a mechanism for downregulation of tumor-suppressor genes [64]

Bound proteins can be precipitated using glutathione resin and eluted by a buffer containing 10 mM glutathione, and then assayed by immunoblotting or mass spectrometry