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These molecules jointly ensure that RBCs can pass through the vasculature without undesired aggregation, while concurrently participating in physiological interactions that facilitate hemostasis and immune surveillance (2, 15, 51)

Because mitochondria are the primary site of ROS production, mitochondrial DNA(mtDNA) and the lipids and proteins that make up the mitochondrial matrix are vulnerable to damage from high levels of ROS (Amaral et al

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10.1056/NEJMoa2312323 96 MengK.JiaH.HouX.ZhuZ.LuY.FengY.et al (2025)

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[DOI] [PubMed] [Google Scholar] 3.Sikiric P, Seiwerth S, Rucman R, Turkovic B, Rokotov DS, Brcic L, Sever M, Klicek R, Radic B, Drmic D, et al