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Furthermore, nude mice injected with NSCLC cells overexpressing miR-486 showed no detectable tumors and decreased IGF-1 level, while control mice formed xenograft tumors
Even successful CAR T-cell therapy may fail to reverse established organ damage in autoimmune diseases, as demonstrated by SLE-related glomerulosclerosis, pulmonary fibrosis in systemic sclerosis, exocrine gland fibrosis in Sjgrens syndrome, and demyelinating lesions in multiple sclerosis
Mitchell2 has shown that particles less than 10 microns should be retained in the respiratory tract satisfactorily
Therefore, it is urgent to enhance the precise regulation of microbial cell factories
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