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Because the symptoms of both conditions overlap so significantly, you might assume your fatigue is thyroid-related when it is actually due to low B12

Kerschensteiner M, Gallmeier E, Behrens L, Leal VV, Misgeld T, Klinkert WE, Kolbeck R, Hoppe E, Oropeza-Wekerle RL, Bartke I, Stadelmann C, Lassmann H, Wekerle H, Hohlfeld R (1999) Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation

Does B12 Affect Mental Health

doi: 10.1111/vsu.13537

Thus, HSPA12B appears to act through both eNOS activation and TLR4 modulation, likely contributing to the mitigation of tissue damage

Most published information currently comes from: While many findings appear promising, additional research is needed to better understand long-term safety, effectiveness, dosing protocols, and potential risks in diverse patient populations