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Mutations in phospholipase DDHD2 cause autosomal recessive hereditary spastic paraplegia (SPG54)

The absence of tissue growth effects also means AOD-9604 avoids many common side effects of growth hormone therapy including joint pain and swelling from connective tissue proliferation, carpal tunnel syndrome from tissue expansion, edema and fluid retention from protein synthesis and sodium retention, and concerns about growth-promoting effects in individuals with tumor history

Journal of Peptide Research

That is clinically meaningful for a specific subset of patients

Injection site irritation may increase slightly since you are adding a daily injection to your routine, but site rotation prevents this from becoming an issue

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