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Description
Vitamin B12 deficiency in hypersecretors during long-term acid suppression with proton pump inhibitors
Kang, J
As reported in an RCT with 64 HT patients, a 6-month treatment with Chuanshanlong Granule (10 g, twice daily) plus L-T4 resulted in a significant reduction in TPOAb and TGAb titers, Th17 cells and relevant cytokines compared to L-T4 alone, as well as in a significant increase in the Treg/Th17 ratio [93]
Standard: Move to 5 mg once daily from day 3 onward
No significant differences were observed between the groups for other immune parameters or GCL activity after supplementation
Formaldehyde dehydrogenase: beyond phase I metabolism
