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For example, Treg cell-specific deletion of phosphatase and tensin homolog (PTEN) causes the hyperactivation of glycolysis and reduces FoxP3 stability, thereby impairing the suppression of Th1 cell and follicular helper T (Tfh) cell immune responses [153]

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the mRNA cleavage/polyadenylation site is flanked by the sequence AATAAA about 12 bp upstream, and a G/T-rich region about 12 bp downstream

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9 Research into mitochondrial metabolism has significantly enhanced our understanding of cancer biology and revealed potential innovative therapeutic targets

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[DOI] [PMC free article] [PubMed] [Google Scholar] Sheppard RC

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Hoffman and Lupica, 2013), as well as GABAergic synapses in hippocampus (Mato et al., 2004)

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