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A serious clinical complication in these patients is the progressive and frequently late-onset dementia noted in this disorder

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91 Berberine may also improve IVF outcomes: 150 women with PCOS undergoing IVF treatment were randomized to receive either metformin, berberine, or placebo for three months before ovarian stimulation

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Furthermore, when 5 M of sapitinib was used, it boosted the potency of paclitaxel by even more (162-fold) compared to the non-resistant parental cell line, SW620
