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However, despite the encouraging evidence, gaps in our knowledge remain to be filled in order to fully understand the mechanisms connecting NNMT with MetS-related disorders and to develop clinical agents against NNMT

Furthermore, it is able to induce apoptosis independently of cross-linking [58]

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2015 5-Amino-1MQ preserves nicotinamide for NAD+ biosynthesis by blocking NNMT-catalyzed methylation, elevating intracellular NAD+ in adipocyte cell lines

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