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2 Literature Search We performed a literature search on 15 October 2023 for English-written articles published up to that date using the National Center for Biotechnology Informations PubMed database ( with the following search terms: gut microbiota AND Parkinson AND therapies OR levodopa OR faecal microbiota transplantation OR diet intervention OR prebiotics OR probiotics, for the latter four using filters for clinical trial and randomised controlled trial (RCT)