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However, the compounds in TGP has low bioavailability and are easy to accumulate in the gastrointestinal tract (Fei et al., 2016)

Our results show a complex reaction mechanism under our experimental conditions and these novelty results will be deeply studied in future approaches

Delton Family Distinguished Professor in Organic Chemistry, and Joshua Munger, professor in the Department of Biochemistry and Biophysics and an expert in cancer cell metabolismare exploring ways to refine potential drugs that could inhibit this process and improve outcomes for patients

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Oral administration results in rapid degradation by gastric acid and hepatic first-pass metabolism, rendering the compounds inactive before reaching systemic circulation