intracellular glutathione oxidative stress system enhancement for cardiac protection: pharmacological options against and ferroptosis Redox State of Glutathione and

This metabolic process, which requires oxygen consumption, contributes to the establishment of anaerobic conditions in the colonic lumen and results in the stabilization of hypoxia-inducible factor-1 (HIF-1) in colonocytes (66)

Cholesterol and Egg Intakes and the Risk of Type 2 Diabetes: The Japan Public Health Center-Based Prospective Study

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On the contrary, some reports demonstrated that high doses of exogenous GSH-reduced cisplatin induce neurotoxicity [37]

In melanoma, the intermittent treatment has already been explored with BRAF and MEK inhibitors in clinical trials (e.g., NCT02583516-completed, NCT03352947-completed, and NCT02196181-active, not recruiting), with the rationale that treatment breaks might alter tumor cell fitness or drug response dynamics