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Additionally, it increases the expression of the peroxisome proliferator-activated receptor (PPAR) and phosphorylated form of AMP-activated protein kinase, improving the regulation of dyslipidemia and increasing lipid metabolism efficiency [130]

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(1990) demonstrated the synergistic interaction between GHRH and GH secretagogues at the pituitary level, providing the mechanistic basis for combining tesamorelin with ipamorelin [2]

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