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Certainly, if left untreated, this gradual decline in oxyhaemoglobin would eventually lead to tissue hypoxia, graft injury, and potential failure

Homeostasis in mitochondrial mass and tissue energetic demands requires biogenic synthesis of new mitochondrial components to be spatiotemporally matched with the removal of old/damaged mitochondria (229)

An alternative strategy is based on targeting tumor necrosis factor alpha (TNF-), a pro-inflammatory cytokine that has increased levels in AD

Antioxidants 9 (8), 645
