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Funding This work was supported by grants from the National Natural Science Foundation of China (NSFC Numbers 81672800, 81603009, 81673020, 81802632, and 82173830), Natural Science Foundation of Shaanxi (2020JQ-445), and the Key Research and Development Program of Shaanxi Province (2021SF-207, 2021SF-223, and 2022ZDLSF05-19)

And where exactly does the needle go

The discipline of waiting for trials, rather than substituting rodent data and case-series enthusiasm for them, is responsible and credible clinical judgement

You have to find some distinctive person in the audience that sits near the stage

Feeling fuller for longer is another benefit