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Programmed necrosis in inflammation: toward identification of the effector molecules

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Isolation of crypts, culture of intestinal organoids and treatments For murine organoid culture: ileum and colon tissues of mice were removed, wash with cold PBS, opened longitudinally, cut into pieces and then incubated on ice in buffer (1xPBS, 8 mM EDTA, 0.5 mM DTT) for 2045 min

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For example, miR-146a down, miR-155 up modulates inflammatory responses in astrocytes epigenetically in neurodegenerative diseases (Yang et al., 2023)

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Meta 12:123 Au WH, Miller-fleming L, Sanchez-martinez A et al (2024) Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction, oxidative stress, and motor phenotypes in C9orf72 ALS/FTD models

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Since the radiation-induced pneumonitis/fibrosis is marked by an inflammatory response, the above observation suggested the probable role of seleno-GPxs in modulating the radiation-induced inflammatory responses (Fig

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NoceraATagliamaccoACioniMInnocenteAFontanaIBarbanoGet alKidney intragraft homing of de novo donor-specific HLA antibodies is an essential step of antibody-mediated damage but not per se predictive of graft loss

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