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Description
Evolution of Negative Cooperativity in Glutathione Transferase Enabled Preservation of Enzyme Function

Other cytokines, such as TGF-, MCP-1, ICAM, and HO-1, also contribute to CIS nephrotoxicity [ 62 , 63 ]

Since vascular growth is not only up-regulated but also accompanied by significant changes in their architecture (i.e., abnormal vasculature, disorganization, etc.) and function [129,130], a tumor burdened with those vessels may eventually be resistant to various therapeutic methods, including systemic treatment in the form of chemotherapy or radiotherapy [131]

Falck J

GPXs are members of a multi-enzyme family that catalyze the reduction of H 2 O 2 , organic hydroperoxides and/or lipid hydroperoxides to generate their corresponding lipid alcohols and water at the expense of oxidation of two molecules of GSH [114]

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