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Researchers must understand the ROS-induced pathogenic pathways that cause organ deterioration and possible countermeasures

GPx4s anti-ferroptosis role is particularly fascinatingby curbing lipid peroxidation, it prevents iron-triggered cell death, relevant in brain injuries or cancers

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doi: 10.1155/2016/3286365

Curcumin also inhibits key signaling pathways and transcription factors associated with viral inflammation, such as NF-B, signal transducer and activator of transcription 3 (STAT-3), Vnt/b-catenin, nuclear factor E2-related factor (Nrf2), and p38/MAPK (419, 420)