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3-bromo-4,5-dihy-droxazole is a natural product-inspired, synthetically accessible electrophilic moiety that has previously been shown to react with nucleophilic cysteines in the active site of purified enzymes

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[DOI] [PubMed] [Google Scholar] 47.Ullian M.E., Gelasco A.K., Fitzgibbon W.R., Beck C.N., Morinelli T.A

Metabolic abnormalities are evident in ME/CFS, such as reduced mitochondrial respiratory function in ME/CFS neutrophils (371, 375) and PBMCs (385)