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The ITT population characteristics at baseline are summarized in Table 1

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Acetyl-l-carnitine treatment increases choline acetyltransferase activity and NGF levels in the CNS of adult rats following total fimbria-fornix transection

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A phase 2 trial of mexiletine, a sodium channel blocker, demonstrated dose-dependent reduction in muscle cramps, though 300 mg doses were associated with fewer adverse events

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