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Besteht die Einnahme von BZD oder BZRA ber einen langen Zeitraum, sollte diese ber mehrere Wochen schrittweise ausgeschlichen werden

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PTEN (Phosphatase and TENsin homolog) is a phosphatase responsible for the conversion of PIP3 to PIP2, acting as an antagonist of the PI3K/AKT response

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This substitution is important for the increased potency of NDP--MSH compared with -MSH

Reviewer information Nature thanks Christian Siebold, Ieva Sutkeviciute, Jean-Pierre Vilardaga and the other anonymous reviewer(s) for their contribution to the peer review of this work